Our main (and everchanging) research goals are to:

• Determine the factors that influence generation, maintenance and function of memory CD8 T cells
                    Nat Immunol 3, 619-626 (2002) / Nat Med 11, 748-756 (2005) / PLoS Pathogens 11, e1005219 (2015)

• Characterize CD8 T cells responding to multiple rounds of antigenic stimulations
                    Immunity 33, 128-140 (2010) / J Immunol 192, 5652-5659 (2014) / Cell Rep 24: 3374-3382 (2018)

• Establish relevant experimental models to study antigen-experienced CD8 T cells in vivo;
                    Immunity 26, 827-841 (2007) / J Immunol 183, 7672-7681 (2009) / Front in Immunol 8: 1527 (2017)

• Investigate the alterations in T cell-mediated immunity that occur after sepsis
                   J Immunol 192, 3618-3625 (2014) / PLoS Pathog 13: e1006569 (2017) / J Immunol 200: 1543-1553 (2018)
   
• Define sepsis-induced state of immunoparalysis and explore treatments to restore immunity in sepsis survivors.
                     J Immunol 197: 4301-4311 (2016) / PLoS Pathog 14: e1007405 (2018) / J Immunol 202: 2843-2848 (2019)